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Methylcobalamin is the naturally occurring, "active" form the body uses directly at the cellular level
A recent meta-analysis of 12 observational studies found that higher dietary intake of vitamin B 12 was associated with a 23% lower risk of depression compared to lower intakes, but stratifying the data revealed a significant protective association in females, not in males (99)
Subcutaneous injections hurt less than intramuscular
With Cyanocobalamin 1000 mcg and other key B-vitamins, Optineuron is widely used to treat neuropathy, neuralgia, neuritis, weakness, and vitamin deficiency states
However, scientific research shows that very high-dose oral B12 (1,000-2,000 mcg) can be effective for some, as about 1% can be absorbed without intrinsic factor
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