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Calcium and ion channels in the endometrium Intracellular ions are known to play an important regulatory role as secondary messengers in many cellular signaling pathways of the female reproductive system [29]
Avoid single-nutrient megadoses unless directed by a clinician
As your body enters a caloric deficit and begins losing weight, some follicles are receiving the signal to transition from anagen to catagen and eventually telogen
But for women who are overweight and have PCOS, even a small amount of weight loss can meaningfully improve reproductive function
On the other hand, administration of tirzepatide at a dose of 70 nmol/kg/day, resulted in a significant weight loss associated with shorter femur compared to saline-treated diabetic mice, but no evident alterations of bone microarchitecture or strength [69]
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