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Spotting: It prevents already produced pigment from reaching the skins surface
Furthermore, potential predictors of affective switching with antidepressants may include bipolar I disorder (versus bipolar II), mixed features during depression, tricyclics and partly dual-action inhibitors versus modern antidepressants [26], rapid cycling and possibly a history of drug abuse, especially stimulant abuse [27]
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Biomedicine & Pharmacotherapy, 132 , 110834
Certain areas (face, trunk) generally respond better than others (hands, feet, lips)
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