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Oral semaglutide (Rybelsus) proves that oral GLP-1 delivery is possible with the right formulation

The maximum penalty applicable is a $2,200 fine and/or 6 months imprisonment, pursuant to section 16

Weight reduction: In the phase 2 trial, cagrilintide 4.5 mg weekly produced approximately 10.8% body weight loss over 26 weeks versus 3.0% with placebo [4]

Because Krystexxa is given intravenously, it would be expected that the great majority of its use would be by rheumatologists rather than by internists or primary care physicians