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It is necessary for fatty acid metabolism and energy production in cardiac and skeletal muscle

Semaglutide has a safety profile, clinical backing, and FDA-approval

Glycyl-l-histidyl-l-lysine prevents copper- and zinc-induced protein aggregation and central nervous system cell death in vitro

Alternative evidence-based interventions, including structured lifestyle programmes, psychological support, other pharmacological options, and bariatric surgery (for those meeting criteria), may be more readily accessible and should be considered as part of an individualised treatment plan

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