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Differential diagnosis at that time included a drug hypersensitivity reaction, and the patient was prescribed triamcinolone 0.1% ointment to apply to the affected areas
That had obvious implications for the treatment of diabetes
Nature 409 , 194198 (2001)
Notably, based on the results from part 1 of the ESSENCE trial, on 15 August 2025, the FDA approved semaglutide 2.4 mg for the treatment of adults with MASH with moderate to advanced liver fibrosis (consistent with stages F2 to F3 fibrosis)
But appetite suppression comes with an underappreciated side effect that relates directly to urinary health
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