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Some people experience vomiting, indigestion, bloating, reflux, headache, fatigue, or abdominal pain, especially during dose changes
However, if there is any concern, confirmatory testing using more specific methods like GC-MS or LC-MS/MS can be employed, which are capable of accurately identifying and quantifying substances present in the sample
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Furthermore, GIPR agonism attenuated the 5FU-induced upregulation of several proinflammatory genes within the ileum, including the immune cell markers adhesion G protein-coupled receptor E1 ( Adgre1 ) and Cd68 , and the cytokines Il1b , Il6 , Tnf , and Ifng (Figure 2J)
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