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Magnesium: Involved in over 300 enzymatic reactions, including collagen synthesis and muscle relaxation

Here's where things get really interesting - and honestly, pretty exciting for most patients

Gross lesions can include hepatomegaly, focal necrosis, single or multifocal, small or large lesions sometimes associated with lesions in other tissues, especially intestines (Percy and Barthold 2007)

Patients and clinicians planning for retatrutide access in 2026 should begin now to frame it within a comprehensive metabolic health program that includes resistance exercise to preserve lean muscle mass during weight loss, protein optimization to mitigate sarcopenia risk, and regular monitoring of body composition rather than body weight alone