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Some semaglutide programs include B12 in the compounded formulation specifically because of the increased risk of deficiency
Under the efficacy estimand, they maintained 100% of that reduction at week 112 compared with 70.5% among those reduced to 5 mg and 44.3% among those switched to placebo
The clinical trials for tirzepatide did not report increased IOP or higher glaucoma risk as common side effects
The study from Eli Lilly demonstrated a mean weight loss of 20.2% with tirzepatide (Zepbound) versus 13.7% with semaglutide (Wegovy) over a 72-week period
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