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MOTS-c modulates the FOXO transcription factors and regulates cellular senescence, the state in which aged or damaged cells stop dividing but refuse to die, instead secreting a cocktail of inflammatory signals known as the senescence-associated secretory phenotype (SASP)
Geletu, M
It's a beautiful example of systemic, holistic regulation
Science 311:622627
A rise in a blood result is not the only consideration
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