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HbA1c values attained a plateau in the 2 groups of patients receiving CagriSema and semaglutide at 20 weeks, whereas in the cagrinlitide group the decrease in HbA1c was more gradual and was progressive up to the end of treatment at 32 weeks [10]
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Several 20242025 systematic reviews and meta-analyses have compiled the cross-trial safety data set (PMID 39318607, PMID 40291085, PMID 40728138)
Although a dual agonist capable of activating both GLP1R and GIPR , Tirzepatide preferentially activates GIPR more, over GLP1R
16 Trial design This was a single-center, randomized, placebo-controlled, double-blind, two-period incomplete crossover trial
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