Structurally, Retatrutide is derived from the glucagon peptide backbone and consists of a 39-amino-acid sequence modified with targeted substitutions that enhance resistance to enzymatic degradation while preserving receptor affinity
Xiao B, Viennois E, Chen Q, Wang L, Han MK, Zhang Y et al (2018) Silencing of Intestinal Glycoprotein CD98 by Orally Targeted Nanoparticles Enhances Chemosensitization of Colon Cancer
Many doctors prescribe Ozempic off-label for PCOS to help with weight, insulin resistance, and metabolic symptoms
And the first big paper that talked about this was actually in Nature Medicine in 2003, and it was originally, I think I should credit Nigel Greig
it produces equivalent results with fewer side effects