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However, reducing equivalents are needed as well in order to activate ERO1 (Kim, Sideris, Sevier, & Kaiser, 2012) and to reduce disulfide isomerases so that they can catalyze reduction of improper disulfide bonds (Schwaller, Wilkinson, & Gilbert, 2003)

Ethics declarations Ethics approval and consent to participate The study protocol was approved by the Independent Bioethics Committee for Scientific Research at the Medical University of Gdansk (NKBBN/354 201/2017)

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