Miura, H., Kusakabe, Y
Sequence Designation: Ipamorelin Ipamorelin is a synthetic pentapeptide with the sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2, designed for selective activation of the growth hormone secretagogue receptor (GHSR-1a)
20, 5271 (2014).CrossRefGoogle ScholarPubMed Liu, J., Zhang, B., Luo, Z., Ding, X., Li, J., Dai, L., Zhou, J., Zhao, X., Ye, J., and Cai, K.: Enzyme responsive mesoporous silica nanoparticles for targeted tumor therapy in vitro and in vivo
HT: Henning Langer #GLP1 #Weightloss #olderadults Thank you for sharing, I believe when Retatrutide enter the market with its triple hormone activity would lower the muscle mass loss compared to older GLPs The distinction between weight-loss-driven lean mass reduction and tissue-specific GLP-1 effects is critical, especially in older adults where baseline sarcopenia prevalence is already high
While the study cannot establish causation, investigators say the results provide a strong rationale for prospective clinical trials evaluating whether GLP-1 drugs could become part of future breast cancer prevention strategies