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One review, which looked at 12 different studies done on centenarians (individuals who live 100 years or more), demonstrated that this long-living group displays lower levels of oxidative stress than other elderly people

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The primary and secondary endpoints of the study were safety and pharmacokinetic parameters, and fasting serum glucose was measured pre-dose and post-dose in study participants, all of whom had glucose and glycated hemoglobin (HbA1c) levels within the normal reference range for the laboratory