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The following are suggested dosages, depending on the condition of the animal and the desired response

AOD-9604 is administered subcutaneously with a half-life of approximately 23 hours in humans (measured in Phase 2 trials), also requiring daily dosing

For instance, the majority (58%) of mouse microbiome studies published in 20182019 did not report the number of mice per cage, and less than 20% of studies reported using singly-housed animals 64

In addition to the lean and ob/ob mice, the study included 3-KO mice and WT controls obtained from genetically verified breeding colonies

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