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While these therapies effectively modulate the inflammatory cascade underlying PsA, accumulating evidence suggests that metabolic factorsparticularly BMImay significantly influence clinical response

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GLP-1 medications work by: Slowing stomach emptying, so you feel full longer Suppressing hunger signals in the brain Increasing insulin release and reducing blood sugar spikes Reducing glucagon, a hormone that raises blood sugar This helps patients lose weight naturally while maintaining balanced blood sugar levels