arthralgia incidence in trials is generally similar to placebo Rapid weight loss from GLP-1 treatment may alter biomechanical loading on joints, causing temporary adjustment-related discomfort Patients prescribed GLP-1 medications often have type 2 diabetes or obesity, conditions independently associated with increased osteoarthritis rates Seek medical advice for severe, worsening, or persistent joint pain, or if accompanied by swelling, redness, warmth, or systemic symptoms Report suspected medication side effects through the MHRA Yellow Card scheme to support ongoing safety monitoring Table of Contents Understanding GLP-1 Medications and Their Common Side Effects GLP-1 receptor agonists, including semaglutide (Ozempic, Wegovy) and liraglutide (Victoza, Saxenda), most commonly cause gastrointestinal side effects such as nausea, vomiting, and diarrhoea

It signals that federal regulators increasingly view GLP-1 therapy as legitimate, evidence-based medicine worth covering, not a lifestyle drug
Does semaglutide give you dry mouth
If you have limited mobility or dexterity, a family member, carer, or healthcare professional can help, or you may prefer using the abdomen or thigh instead
Four studies ( Table 1 and Supplementary Table 6