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Furthermore, this process inhibits the expression of lipogenesis-related genes, ultimately enhancing ketogenesis (27, 28)

It may help maintain weight loss after GLP1 tapering in the first few months, but its use is often limited to short-term, in part because it is a schedule IV controlled substance due to its stimulant nature and has potential for abuse

Researchers said the effectiveness of a once-weekly dose of semaglutide to treat type 2 diabetes has been demonstrated in randomised controlled trials, but long-term data has been lacking

These opposing effects might seem like they would cancel each other out

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