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6 Metformin may reduce HbA1c by 1.8% to 2% in patients with respective hyperglycemia
The anatomical distribution of GLP-1R throughout the reproductive system and several preclinical evidence support that GLP-1 can modulate the HPG axis activity at different levels, thus connecting reproductive functions, metabolic system, nutrition, and energy homeostasis mechanisms
Both are within the 28-day stability window
Effect of GLP-1 receptor agonists on heart rate in non-diabetic individuals with overweight or obesity: a systematic review and meta-analysis
Most importantly, providers should help patients understand that treatment plateaus do not represent failure
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