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In a statement made earlier this year, Dave Moore, executive vice president of US Operations at Novo Nordisk said: As the FDA has warned, compounders cannot rely on mere pretextual differences between unapproved compounded drugs and FDA-approved medicines under the guise of making personalized drugs in order to evade federal law. Likewise, Lilly intends to monitor the situation: There is no generic version of Mounjaro or Zepbound, Lillys FDA-approved tirzepatide medicines, and mass compounding of tirzepatide is unlawful, says the Lilly spokesperson

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The states with the highest prescribing rates are also among those with greater prevalence of diabetes and obesity, per CDC data, a rough indication that the medicines may be getting to areas where they are in greatest need while shortages, high price tags and insurance restrictions have limited their use