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Fortunately, new medications like tirzepatide and semaglutide have changed the landscape of weight management, offering substantial clinical benefits
Source: Barrett, et al JAMA Surgery, September 17, 2025 Researchers correlated insurance claims data and electronic medical records in a system that owns both an insurance plan (Highmark) and a provider system (Allegheny Health), and compared total medical expense for over 30,000 individuals who had either metabolic and bariatric surgery (sleeve gastrectomy) or were treated with GLP-1 medications between 2018 and 2023
Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug
And if you are wondering whether tirzepatide needs to be refrigerated at all, the answer depends on the specific formulation your pharmacy uses
Cold water, herbal tea, and broths work well
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