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Of the other phenotypes like convenient diner, fast-pacer, self-critic, all-or-nothing doer the medications don't tackle those really at all

The interplay among oxidative stress, brain insulin resistance and AMPK dysfunction contribute to neurodegeneration in type 2 diabetes and Alzheimer disease

Sarris AH, Kliche KO, Smith T, Preti A, Messina O, Hess M, Pugh W, Andreeff M , Cabanillas F

The Medical clinics of North America, 102(1), 183197

505,506,507 ARIs Epalrestat is an aldose reductase inhibitor that prevents the accumulation of sorbitol and fructose within nerve cells, which can cause osmotic stress and neuronal damage