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Questa riduzione potrebbe essere uno dei fattori alla base del declino delle capacit rigenerative dellorganismo
[ii] - Ondrej Zitka, Sylvie Skalickova, Jaromir Gumulec, Michal Masarik, Vojtech Adam, Jaromir Hubalek, Libuse Trnkov, Jarmila Kruseova, Tomas Eckschlager and Ren Kizek: Redox status expressed as GSH:GSSG ratio as a marker for oxidative stress in paediatric tumour patients
By raising NADPH and glutathione levels, NO lowers ROS levels and promotes glutamine and TCA cycling in ovarian cancer cells (105)
It remains unknown why this aggregation occurs
Moreover, the expression of key spermatogenesis markers, including UCHL1, PLZF, SCP3, and PCNA, which were reduced in aged testes, were significantly restored or increased following FOXO4-DRI treatment
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