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Rapid Clearance Kinetics Like most linear peptides under 2 kDa, AOD-9604 is subject to rapid enzymatic degradation by serum peptidases and renal filtration [7]

2001, AOD-9604 lost most of this fat-metabolism effect in mice that were genetically missing the beta-3 adrenergic receptor, suggesting that pathway carries part of the signal

The compound is primarily associated with research involving nicotinamide N-methyltransferase (NNMT) , an enzyme that participates in metabolic reactions involving nicotinamide and methyl donor molecules

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