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Although epidemiologic studies have shown an association between vascular disease and hyperhomocysteinemia, large randomized controlled trials have shown that lowering homocysteine levels in these patients does not reduce the number of myocardial infarctions or strokes, or improve mortality rates

The NHS Digital Weight Management Programme typically requires a BMI 30 kg/m (or 27.5 kg/m for certain ethnic groups) plus additional risk factors such as diabetes or hypertension

We Just need a lot more human trials, like phase one, phase two, phase three

An upper intake level of 2 g/day was set to avoid diarrhea and gastrointestinal disturbances with high supplemental intakes

This makes sense physiologically