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while respiratory viral infections cause antioxidant enzyme expression/activity inhibition associated with reduced Nrf2 nuclear localization, decreased cellular levels and reduced ARE-dependent gene transcription (Komaravelli and Casola, 2014)
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N-acetylcysteine, an efficient thiol antioxidant and GSH precursor, was able to inhibit ATG by impeding the lipidation process of LC3 mediated by ATG4, the activity of which is modulated by hydrogen peroxide (Scherz-Shouval et al., 2007)
Antioxid Redox Signal 2002
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