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The role of metabolism in chondrocyte dysfunction and the progression of osteoarthritis
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For decades, mitochondria were studied almost exclusively as disease targets: their dysfunction was documented in Parkinson's disease, in heart failure, in type 2 diabetes, but the therapeutic response was always indirect
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Thus, we propose that the polar bond between Asn205 and the hydroxyl group of HQ indicates on an inhibitory effect on TyrBm
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Effect of l-carnitine on diabetes-induced changes of skeletal muscles in rats
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They target the same broad NAD+/SAM biology from different directions, which is why they are sometimes discussed together
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