To qualify to take Ozempic for weight loss (off-label), you must have a BMI of 30 or higher or a BMI of 27 or higher and at least one weight-related condition, such as high blood pressure or high cholesterol
In peripheral tissues, they can be found in adipocytes, cardiomyocytes, and osteoblasts as they are essential for glucose-insulin homeostasis, gastrointestinal motility, cardiovascular health, inflammation, and tissue growth and repair (4)
Proc Natl Acad Sci USA 1995;92:81159
In a sensitivity analysis excluding the SELECT trial, which was the only study enrolling pre-diabetic participants, the reduction in MACE remained consistent (HR (95% CI): 0.87(0.820.93)
Obesity as pleiotropic risk state for metabolic and mental health throughout life