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Most clinical guidelines suggest that there is no direct contraindication for using semaglutide in patients with common, benign (non-cancerous) thyroid conditions like hypothyroidism or Hashimotos disease

It can also modify proteins by incorporating homocysteine instead of methionine into the proteins

This dual action of stimulating insulin and suppressing glucagon helps lower blood sugar more effectively

Jensen MT, Nielsen SS, Jessen-Winge C, Madsen CMT, Thilsing T, Larrabee Snderlund A, et al

Clinical trials have demonstrated substantial improvements in hemoglobin A1c reduction (up to 2.5% decrease) in diabetes patients, while weight loss of up to 20% was observed primarily in adults with obesity without diabetes in the SURMOUNT-1 trial