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Wegovy (semaglutide) is not formally contraindicated post-cholecystectomy, but your prescriber should evaluate your post-surgical symptoms individually

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ChaC2 typically exists in dimer crystals with a unique flexible loop 2 structure, with an open conformation that can facilitate close contact with crystallographically adjacent ChaC2 molecules

Examining the full (unmatched) cohort for MOF risk yielded a significant protective effect in the GLP-1 RA group (unadjusted HR 0.67 [0.580.78]) compared to the DPP-4i group