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Lactoferrin was also effective in treating pregnant women with iron deficiency anemia: Oral administration of lactoferrin (100 mg/twice a day for 30 days), that was iron-saturated to 30%, increased the total serum iron and hemoglobin concentrations to a greater extent than administration of ferrous sulphate (156 mg/day) in 60 anemic women (Paesano et al., 2009, 2010)

The peptide backbone provides three coordination sites for copper: the free alpha-amino group of glycine, the deprotonated amide nitrogen of the glycyl-histidyl bond, and the imidazole nitrogen of the histidine side chain, with the lysine epsilon-amine remaining available for further interactions

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The results revealed that DFO pretreatment reversed the increased Ptgs2 and decreased levels of Slc7a11 and Gpx4 induced by CME (Figures 2AF)