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diff risk), family history, and red flags
The existence of metabolomic alterations and chronic systemic inflammation even 12 months after acute SARS-CoV-2 infection suggests a dysregulated immune response
Third, the optimal positioning and sequencing of GLP-1-based therapies relative to resmetirom and other emerging MASH agents (e.g., lanifibranor, pegozafermin, semaglutide combination regimens) requires dedicated combination trials, of which preliminary data from the MAESTRO-NASH secondary analysis are encouraging
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