FDA-approved GLP-1 receptor agonists include semaglutide (Ozempic, Wegovy), liraglutide (Victoza, Saxenda), and dulaglutide (Trulicity)
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Overall, GLP-1 medications appear to be safe in older adults, and the rate of serious side effects is similar to what we see in younger people
In patients with overweight or obesity (mean age 50.1 years, 72.6% female), semaglutide compared with non-GLP1R agonist anti-obesity medications was associated with lower risk for incident (HR = 0.27, 95% CI = 0.200.320.600.36) and recurrent (HR = 0.44, 95% CI = 0.320.60) suicidal ideation, consistent across sex, age and ethnicity stratification
10.1016/j.lfs.2021.120058 34 De BosscherR.DausinC.ClausP.BogaertJ.DymarkowskiS.GoetschalckxK.et al (2023)