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In a pilot study run in 2001 that included 20 non-diabetic patients, a 4-month course of metformin was associated with an improvement in serum aminotransferase levels, insulin sensitivity, and liver volume detected with ultrasound (US) in patients with NAFLD
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10.1016/j.cell.2007.03.045 9 Tait S
Zhang et al., 2022), and chronic kidney disease (Hsu et al., 2020)
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