Waist circumference, progress photos, how clothes fit, energy levels, sleep quality, and blood markers all contribute to the full before-and-after picture
Lost 10lbs
A maintenance strategy matters: nutrition, resistance training, follow-up, medication adjustment, dose reduction, switching, or continued therapy depending on the patient
The SUPRPASS-4 trial (262), involving 2002 participants with high-risk cardiovascular profiles followed for up to 104 weeks, showed no difference in 4-MACE events (cardiovascular death, myocardial infarction, stroke, and hospitalization for unstable angina) with tirzepatide compared to insulin glargine (HR 0.74
Regular physical activity, even simple walking, also helps stimulate bowel movements and supports overall gut health