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Semaglutide is approved for treating type 2 diabetes, but it is increasingly prescribed off-label for weight loss
You feel like your blood sugar is low
therefore, informed consent was not required
Cognitive function in obese individuals improves substantially with weight loss alone, but the direct central GLP-1R effects may contribute additional benefit beyond what weight reduction alone would predict
Considering the relationship between GLP-1 signaling and behavioral symptoms characteristic of depression, it was shown that intracerebroventricular ( icv ) administration of both GLP-1 and exendin-4 enhances associative and spatial learning, while these effects are inhibited by a GLP-1R antagonist
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