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In animal models, GLP-1R agonists prevent capillary rarefaction and microvascular barrier dysfunction and reduce apoptosis and reactive oxygen species in microvascular endothelial cells, contributing to improved organ function and reduced progression of microvascular complications [162]

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The inclusion of six population-based cohorts from diverse geographical settings enhances the generalizability of the findings. The authors also remarked that, The median follow-up period of 1.8 to 3.0 years is insufficient to evaluate long-term risks. In addition, the studys focus on populations with type 2 diabetes may limit is applicability to non-diabetic populations, a growing group of GLP-1RA users, particularly for obesity management. About the Journal Thyroid , the official journal of the American Thyroid Association , (ATA ) is an authoritative peer-reviewed journal published monthly online with open access options and in print

Hwang, P