glp 1 agonist GLP-1 agonists approved for clinical use. GLP-1 agonists are available Current Insights, Advantages and Challenges

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doi: 10.3390/medsci6020047 86 SabirinF.LimS

The SGLT2 inhibitor empagliflozin orchestrates protective multisystem (cardiovascular, kidney, metabolic and hepatic) effects by reprogramming cellular energetics, normalizing haemodynamics and activating cytoprotective pathways that limit oxidative stress, fibrosis and inflammation

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Wyckelsma VL, Levinger I, McKenna MJ, Formosa LE, Ryan MT, Petersen AC et al (2017) Preservation of skeletal muscle mitochondrial content in older adults: relationship between mitochondria, fibre type and high-intensity exercise training: high-intensity training in elderly humans