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Despite their popularity, its crucial to approach these treatments with informed caution, considering the varying degrees of scientific support and the importance of professional medical guidance
For example, a novel dual agonist of GLP-1/GIP receptors significantly increased BDNF levels in a mouse model of Parkinsons disease, induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration [53]
This mechanism can drive weight gain after withdrawal of drug therapy and as food intake returns to ad libitum levels
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