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A large systematic review that examined 8 studies (910 women) found that NAC treatment (either alone or in combination with metformin a diabetic drug commonly used in PCOS) notably boosted pregnancy success rates ( 13 )
These minor side effects include dizziness, sleepiness and changes in blood pressure ( One major adverse event occurred during one of these tests, which resulted in the death of an individual with high blood pressure but good health otherwise ( However, it seems likely that an accidental overdose of approximately 70 times the recommended intake caused the complications ( Overall, it appears that methionine is not particularly toxic in healthy humans, except at extremely high doses that would be virtually impossible to obtain through the diet
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