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doi: 10.1016/j.bcp.2023.115673 87 GraingerJRKonkelJEZangerle-MurrayTShawTN
When a patient plateaus or fails to respond, the question shouldn't be "increase the dose?" but "what has changed metabolically?" Measuring resting energy metabolism and substrate utilisation provides a prospective way to identify metabolic adaptation, personalise nutrition, preserve lean mass and guide treatment before outcomes deteriorate
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