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Generally, gut dysbiosis contributes to the pathogenesis of NAFLD by leading to leaky gut, bacterial translocation and low-grade inflammation related to endotoxemia (68, 69)
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Gastrointestinal effects are the reason a lot of people quit GLP-1 treatment in the first few weeks, often before the medication has had a chance to do much of anything
Incorporating these lifestyle changes can drastically improve quality of life when maintained alongside the medication
Additionally, treatment with GLP-1RAs was found to upregulate the expression of pulmonary surfactant proteins A and B, contributing to improved respiratory physiology (Wang et al., 2023b)
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