In aged rat models, treatment increased activity of antioxidant enzymes like superoxide dismutase (SOD), glutathione peroxidase, and glutathione-S-transferase, improving overall oxidative defense
People with irritable bowel syndrome (IBS) or certain other conditions may experience diarrhoea more frequently than others
Also, persons with health conditions like HIV, celiac disease, and Crohns disease may find it difficult to absorb vitamin B effectively
This could also address an area of concern for roughly two-thirds of physicians who question whether non-traditional telehealth providers offer sufficient oversight when prescribing GLP-1s , per a December 2025 Sermo survey
Losing too much muscle during weight loss creates a cascade of problems that can undermine the very goals that prompted someone to start semaglutide therapy in the first place