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2 How to Prevent and Minimize GLP-1 Nausea 1 1 Taking proactive steps with your medication and diet can help you avoid nausea or reduce its severity: Medication Management Start Low, Go Slow: Most GLP-1 medications including Ozempic, Wegovy, Mounjaro and Zepbound are first prescribed at a low dose and gradually increased over several weeks or months

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However, the moment you experience vomiting, severe diarrhea lasting more than a few hours, or inability to tolerate any food, it's time to hold that week's dose and contact your healthcare provider

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