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Insulin resistance is what happens when the cells in your muscles, fat, and liver don't respond well to insulin and can't use glucose (i.e., sugar) from your blood for energy, per the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

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Where the research could go next Open scientific questions remain

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This localized depletion is strongly correlated with increased ventricular lactate, pointing to severe neuroinflammation, an overwhelmed central nervous system antioxidant network, and a direct physiological explanation for the profound cognitive dysfunction and "brain fog" experienced by patients