doi: 10.1038/s41422-021-00569-8
Its difficult to quantify how much someone could lose on Wegovy, as this depends on many factors, such as underlying health conditions, starting weight, any other medications you may be taking, and various other things
Heartburn on GLP-1 may improve with: Smaller meals Lower-fat meals Avoiding late-night eating Staying upright after meals Reducing carbonated drinks Limiting alcohol Avoiding trigger foods such as spicy meals, fried foods, chocolate, or peppermint if they worsen symptoms Discussing persistent reflux with a clinician Do not assume all upper abdominal discomfort is simple reflux
Tirzepatide Level 2 is required for patients requiring dosing exceeding 10 mg/week
Published protocols also note pregnancy, known hypersensitivity to IGF-1 analogs, and pre-existing insulin resistance or diabetes as conditions requiring exclusion or enhanced monitoring in study design