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Materials and methods Animals Adult (810weekold), male C57BL/6 mice (Jackson Laboratories, Bar Harbor, ME) weighing between 20 and 25 g were used

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GSH inhibits PSC activation induced by high glucose via the ROS/TGF/SMAD pathway in vitro The above results indicated an increase in pancreatic fibrosis in rats treated with LOsG, which was accompanied by an increase in ROS/TGF/SMAD signalling, and PSC proliferation and activation, which were all prevented by GSH

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nicotine and flavoring aerosols also drive oxidative stress