2 Tirzepatide, the drug in Mounjaro, interacts with the brain area responsible for our sleep/wake cycle: Its possible Mounjaro is having an indirect effect on our brains internal clock, interrupting our normal sleep patterns, and making us feel more tired than usual
She lost about 60 pounds and discovered an unexpected side effect: She used to enjoy drinking socially, but lost interest in alcohol after starting the medication
What Semaglutide Is (GLP-1 Receptor Agonist Explained) Semaglutide is a synthetic version of a naturally occurring hormone called glucagon-like peptide-1 (GLP-1)
Due to a short plasma half-life of native GLP-1, several synthesized GLP-1 receptor agonists (RAs) were developed for type 2 diabetes mellitus (DM) treatment
Last reviewed: July 8, 2026 Last updated: July 8, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations