Results Cystine availability regulates mTORC1 signaling and the ISR We studied the effect of cystine starvation in HepG2 cells, which do not synthesize cysteine from methionine, to exclude the confounding effect of methionine 20
Neuron 108 , 11461162.e1110 (2020)
Sources: GLP-1 Pipeline Update: May 2025 - Prime Therapeutics - Portal, clinicaltrials.gov, Analytics Link
Turnbull FM, Abraira C, Anderson RJ, Byington RP, Chalmers JP, Duckworth WC, Evans GW, Gerstein HC, Holman RR, Moritz TE, et al
While more studies are needed, current evidence supports their potential to reduce CV risk through multiple direct and indirect mechanisms, offering hope for improved outcomes in a population with historically elevated premature mortality